Purified proteins are essential in research laboratories for applications such as 3D structural analysis (X-ray, cryoEM, NMR), interaction studies, and cell biology experiments. They also play a key role in characterising enzymatic activities and are widely used in therapeutic and diagnostic industries. Ensuring reliable experimental data requires strict protein quality control. In 2021, the ARBRE-MOBIEU and P4EU networks published guidelines for evaluating purified proteins in life sciences and medical research. This course introduces these guidelines and explores technologies that enhance data accuracy and reproducibility, combining theoretical knowledge with hands-on experience.

With the support of the International Union for Pure and Applied Biophysics (IUPAB)

The International Union for Pure and Applied Biophysics (IUPAB), established in 1961, is a global organisation dedicated to advancing biophysics research and education. It comprises national adhering bodies from 61 countries and is affiliated with regional associations such as the European Biophysical Societies' Association (EBSA) and the Asian Biophysics Association.

IUPAB's core functions include organising triennial international congresses, such as the upcoming 2024 Congress in Kyoto, Japan, and the 2027 Congress in Berlin, Germany. The organisation also sponsors conferences, schools, and workshops to support research and teaching in biophysics. Additionally, IUPAB offers bursaries to early-career scientists, especially from less-developed countries, to facilitate their participation in relevant scientific events.

To recognise outstanding contributions in the field, IUPAB presents awards such as the Avanti-IUPAB Prize and the Young Investigator Prize. The union also publishes Biophysical Reviews, a journal featuring critical reviews from leading figures in biophysics. Through these initiatives, IUPAB fosters international collaboration and the application of biophysics to address global challenges.

This course introduces quality control guidelines established by the ARBRE-MOBIEU and P4EU networks. Participants will learn practical techniques to assess protein quality and enhance data accuracy through a combination of theoretical lessons and hands-on sessions.