Automated titrations

Allowing for fully programmable, unattended, step-wise addition of titrant, this Chirascan accessory allows following spectral changes in dependence of, e.g., concentration or pH. Available for manual Chirascan systems.

An accessory to expand the capabilities of your manual Chirascan system

  • Carry out chemical denaturation experiments by step-wise addition of denaturant such as urea or guanidine hydrochloride
  • Determine binding constants for ligand binding studies
  • Perform pH titrations together with the Chirascan pH Probe accessory

Chirascan SYSTEMS


Chirascan pH Probe accessory



Features and Specifications

Compatible with Chirascan VX and Chirascan V100

Accuracy and precision
  • Syringes driven by high-precision stepper motors
  • Accuracy: up to ±10 μL of dispension/aspiration*
  • Precision: up to ±2 μL of dispension/aspiration*

*For standard 1 mL syringe; see user manual for other syringe sizes

  • Sample homogeneity ensured by mixing with magnetic stirrer (included in all manual Chirascan systems)
  • Typical sample volume: 1.8 to 3 mL (10 mm path length cuvettes only)
  • Single- and dual syringe modes with/without sample withdrawal for constant sample volume or titrant concentration steps
Included components
  • Titration unit
  • Two 1 mL syringes
  • Tubing with sinkers and cuvette adapter
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